The novel fusogenic peptides improve the delivery of therapeutics for ovarian cancer through their ability to enhance endosomal escape and delivery of bioactive therapeutics. Epithelial ovarian cancer is the 5th leading cancer among women, with a 49% five-year survival rate. Current treatment strategies for ovarian cancer include surgical removal, chemotherapy, and radiation; however, these treatments often prove ineffective or toxic…
Inventor: Angela Alexander-Bryant, Timothy Samec
This orthopedic method and device quantifies contact stress and contact area in total joint replacements. The American Academy of Orthopedic Surgeons has reported that annual hip and knee joint replacements have risen to over 2 million procedures within the United States alone. These implants have a typical lifespan of 10 years before needing to be replaced due to the wearing…
Inventor: Martine LaBerg, Andrew Clark
Clemson University researchers have developed an in vitro
myocardial therapy screening platform possessing superior
physiological relevance that enables clinically translatable metrics
for therapy efficacy and cardiotoxicity evaluation.
Inventor: William Richardson, Samuel Coeyman, Jonathan G. Heywood
Advanced Materials, Biomedical
Clemson University researchers have developed new delivery and attachment systems for a previously invented collagen-based patch that promotes natural healing of the IVD.
Inventor: Jeremy Mercuri
Clemson University researchers developed a new design that provides an alternative surgical treatment to arthrodesis.
Inventor: John DesJardins,