Medical Devices

Medical Devices

Fusogenic Peptides for Delivery of RNAi Therapeutics to Ovarian Cancer


The novel fusogenic peptides improve the delivery of therapeutics for ovarian cancer through their ability to enhance endosomal escape and delivery of bioactive therapeutics. Epithelial ovarian cancer is the 5th leading cancer among women, with a 49% five-year survival rate. Current treatment strategies for ovarian cancer include surgical removal, chemotherapy, and radiation; however, these treatments often prove ineffective or toxic…

Orthopedic Method and Device that Measures Dynamic Contact Pressure and Area in Artificial Joint Implants

Biomedical, Biotechnology

This orthopedic method and device quantifies contact stress and contact area in total joint replacements. The American Academy of Orthopedic Surgeons has reported that annual hip and knee joint replacements have risen to over 2 million procedures within the United States alone. These implants have a typical lifespan of 10 years before needing to be replaced due to the wearing…
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