Advanced Materials, Biomedical, Biotechnology
This technology applies to the isolation, purification, and recovery of extracellular vesicles from plant materials, referred to as plant-derived extracellular vesicles. The exosome population of the PDEVs are employed for use as vectors for the delivery of therapeutics. Exosome vectors are a promising means for the treatment of many diseases, many of which are currently in clinical trials. Roots Analysis…
Inventor: Richard Kenneth Marcus, Kaylan Jackson, Carolina Mata
This patient risk-assessment machine learning algorithm predicts patient response to cardiac resynchronization therapy (CRT) intervention enabling more informed selection criteria and improved rates of therapy success. Approximately 90,000 patients receive cardiac resynchronization therapy per year, with only 50% of that population benefitting. This directly results from the uncertainties surrounding which patients will actually benefit from the procedure. Providing insights into…
Inventor: Will Richardson, Anamul Haque, William Douglas Stubbs Jr.
Clemson University researchers have developed an in vitro
myocardial therapy screening platform possessing superior
physiological relevance that enables clinically translatable metrics
for therapy efficacy and cardiotoxicity evaluation.
Inventor: William Richardson, Samuel Coeyman, Jonathan G. Heywood
Clemson University researchers have developed an anti-biofouling approach that can inactivate bacteria without introducing chemicals into the feed water and without pausing operation of the membrane treatment process.
Inventor: Ezra Cates
Clemson University researchers have developed a new family of modified small molecules that include bisbenzimidazole derivatives as antimicrobials and topoisomerase inhibitors.
Inventor: Dev Arya, Nihar Ranjan, Fenfei Leng