Skip to content

Market Overview

Scrybe utilizes Lightweight Mining (LWM) which allows the algorithm to depart from the
resource-intensive and time-consuming verification approaches that cryptocurrencies use when
expanding the blockchain. The clinical trials market size is expected to reach 68.9 billion by
2026, growing with a CAGR of 5.7%. Digitization is rapidly being adapted by securely maintaining
patient data records, which lowers cost and reduces process errors. Ensuring that trial data is
securely stored is essential to meet stringent regulations from governing bodies like the FDA.
Scrybe also prevents malicious manipulation of data and is not dependent on local policy. This
allows auditors to verify the integrity of the stored data, and the data integrity and non-
repudiation are guaranteed.


Clinical trials, information security, Data Management

Technical Summary:

Scrybe has two main components: blocks and transitions. Blocks are added to the
blockchain by authorized miners. Transactions can reference previous transactions,
providing a chain of custody, or they can be genesis events, which register the acquisition
of new data. Both patient information and permissions are collected and stored on a local
server controlled by the medical institution. Using non-sensitive meta-data, a transaction is
created on the secure server and a permanent universal resource locator (PURL) is created
pointing to the data. The transaction is signed and submitted to miners. These miners add
the transaction to a block which is then added to the blockchain where it can be broadcast
to other miners for verification. Raw data is collected and stored locally on a secure server.
This process is repeated as more information is generated and subsequently associated
with the original transaction. This allows auditors and researchers to access the findings of
other teams by viewing transaction records within the blockchain complete with signature
for data verification.


  • All data is digitally signed ensuring integrity and allowing it to be tracked
  • Improved energy efficiency and lower cost
  • Can tolerate a larger percentage of malicious actors

Download Printable PDF

Technology Overview

State of Development

Ready for Licensing

Patent Type



Information and Communication

Serial Number


CURF Reference No.



Dr. Robert Brooks, Dr. Lu Yu

For More Info, Contact:

Interested in this technology?
Contact curf@clemson.edu
Please put technology ID in subject line of email.


Get Started
Ready to Get Started?

Contact our team at CURF

Contact CURF