Advanced Materials, Biomedical, Biotechnology
This technology applies to the isolation, purification, and recovery of extracellular vesicles from plant materials, referred to as plant-derived extracellular vesicles. The exosome population of the PDEVs are employed for use as vectors for the delivery of therapeutics. Exosome vectors are a promising means for the treatment of many diseases, many of which are currently in clinical trials. Roots Analysis…
Inventor: Richard Kenneth Marcus, Kaylan Jackson, Carolina Mata
The novel fusogenic peptides improve the delivery of therapeutics for ovarian cancer through their ability to enhance endosomal escape and delivery of bioactive therapeutics. Epithelial ovarian cancer is the 5th leading cancer among women, with a 49% five-year survival rate. Current treatment strategies for ovarian cancer include surgical removal, chemotherapy, and radiation; however, these treatments often prove ineffective or toxic…
Inventor: Angela Alexander-Bryant, Timothy Samec
Clemson University researchers have developed an in vitro
myocardial therapy screening platform possessing superior
physiological relevance that enables clinically translatable metrics
for therapy efficacy and cardiotoxicity evaluation.
Inventor: William Richardson, Samuel Coeyman, Jonathan G. Heywood
Clemson University researchers developed a new design that provides an alternative surgical treatment to arthrodesis.
Inventor: John DesJardins,
Clemson University researchers have developed a biomaterial that mimics the structure and function of human NP to mitigate or halt progression of IDD.
Inventor: Jeremy Mercuri, Christopher Fernandez