Inventor Spotlight: Narendra Vyavahere

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October 29, 2019

Dr. Naren Vyavahare, a Hunter Endowed Chair and Professor of Bioengineering at Clemson University, is transforming healthcare through his research in cardiovascular disease pathology, heart valve biomaterials, site-specific therapies, and extracellular matrix remodeling in tissue regeneration. Growing up in Pune, India, in a middle-income family, Vyavahare believed that education was the key to his and his family’s future. As a result, he earned his Ph.D. in Chemistry at the University of Pune in 1990. Prior to joining Clemson, Vyavahare served as a Research Assistant Professor at the University of Pennsylvania School of Medicine and as a Research Investigator at the University of Michigan.

Since joining the Clemson family, Vyavahare has received more than $34 million in federal funding, including a National Institutes of Health (NIH) Centers of Biomedical Research Excellence project grant that has drawn in more than $25 million since 2009, making it the largest single grant in Clemson’s history. He is currently serving as the director of the South Carolina Bioengineering Center of Regeneration and Formation of Tissues (SC BioCRAFT), and has launched three biotechnology companies based on its work. 

Vyavahare has made major contributions to heart valve implants and understanding the mechanisms of vascular calcification, for which one of his treatments is now clinically usedHis current research, funded by the NIH, focuses on finding targeted treatments to stabilize and restore vascular structures to prevent or reverse calcification, aortic aneurysms, chronic obstructive pulmonary disease (COPD), and skin disorders. Vyavahare’s research has been published in over 150 journals and conference proceedings, in 6 book chapters, and has resulted in 13 international and US patents—some of which are now licensed to companies to develop products. In addition to his research, Vyavahare has a passion for developing the next generation of inventors. During his time at Clemson, he has graduated 13 Ph.D. students and 20 M.S. students. 

Helping people continues to be the overarching theme of Vyavahare’s research. He believes that innovative research is the key to improving the lives of millions of people, and as a result, constantly works to make a difference in the world with his research. 

To learn more about Dr. Vyavahare, click here.

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