Those with inherited metabolic diseases face obstacles to everyday life that often include pain. To combat this, Dr. Renee Cottle has dedicated her research to developing cell-based gene therapy technologies and point-of-care devices to improve the lives of those with this disease. Cottle received her Ph.D. in Biomedical Engineering from the Georgia Institute of Technology and Emory University in 2015 and is currently an Assistant Professor of Bioengineering at Clemson University.
Prior to coming to Clemson, Dr. Cottle spent years working as a Graduate Research Assistant at the Georgia Institute of Technology. While in this position, she investigated methodology for safely and effectively delivering β-globin-aiming TALENs and CRISPR/Cas9 systems for genome editing of a sickle cell disease mutation as a novel therapeutic strategy. At Clemson, her current research explores gene editing approaches to treating disease, ex vivo gene editing, and 3D culture platforms in hepatocytes.
In addition to her research, Cottle has been the recipient of numerous awards such as the 2021 Pinnacle Research Award from the American Association for the Study of Liver Disease Foundation, the 2018 Biomedical Engineering Society Career Development Award, and the 2014 Ford Dissertation Fellowship Honorable Mention from the National Academies of Sciences Engineering Medicine.
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